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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2322e8cadff79704650b53e7a8050406afc86f56c679bdf25567f265ae8c2d29' 
  AND token = '6OOf69mIa5pxLpgaowk4M00UgurG8yzw74TquLnGtVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}