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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '53b08291532b6074ce4a3cbef0537786be414bb3191e48cf3a9ef7fd7b428f15' 
  AND token = '9cMtred/BURSysNjtWFMdySvG4UmI8nGrRJgtBODuAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}