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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a50343e921ddd38ffe1abe6f1c918e0f73d408cf5ed24f37f1afc39428214150' 
  AND token = 'ROgQD1nmFz8/HpT6rrF4d/bnSosX/wFW/a1mI5xtuAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}