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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '66e3b4af2f576812e44a42dada7d37bb77fc4bb2b8bb9774a3212dce35a487ff' 
  AND token = 'F2zM9/CIQweh85SIVuc7HzCc+CGbh5hEFCG9Z4lod3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}