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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4459ac7b43dc674661e0287f89bd0ff184bc9737b5da47ff15c8febcb5753d2b' 
  AND token = 'mL377fvkXyzXZF0HJAH0zzsRMw5N4COdNMizha/IgoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}