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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '279a6c43ef6525c726f1cd9d3c96315adc006e8998d1795025e75ba073ab888c' 
  AND token = 'w930S4LQ3Afm1FVy+lBY/DBLYxHE8eazuzIayxJ3DW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}