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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ea0cc5010e13fc81cae507bc5209215fe1930d35aadcc20d8868de91c7642c81' 
  AND token = 'GyfI5byb33Y1e73HJWItSxhbhxDhhsihXQujMWPkjQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}