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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b224529dbc65ddfd4f177e2dbfb37d87893085906b97c4b612eb260eddcab947' 
  AND token = 'O2pFEi1Wko15bM/gj39smO8mS0xxITntI94Mp09SqsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}