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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3239f22294dcea922b7d7fc6e5b8eca625d8fd3e7f3285666439e1740fefe523' 
  AND token = 'R1WiB7CRu0wfTjoGEFexoaVgq3uJ6d+0OD8TdTvAsIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}