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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a2c430e880be9fec47d0f6c009acb5d34c293a31e9cbbdc65f6c4aecc44a7a9c' 
  AND token = 'kwjBiYUrBMuQCYATjwVs/wDM4ictjeU5jDQAmbSo3fU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}