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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0c45338d0e042d60d4e110b33a626c89dcc78a6bd9d84f9ceacb71727a139635' 
  AND token = 'vvOi+RAgkEEqbVoIOKqgjt1soP9eqb57nOBdWOOcqkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}