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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '64d559226d2c7c7519000d0d71a300fdfb64983a255f22c186b23a04d953debf' 
  AND token = 'FPCPrCOOQU4B/e4XKFBCxVrEXXd5iGH7BJIeLPXNIP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}