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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0f2f417fa719af5bd81df74697bc5dda9a4c3dcddd254bcfba32f74b29f9574a' 
  AND token = 'TR+2qcvrxWJkReTqGJDGdsRgPIjKN0UzDpWW9oMCE6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}