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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8f963e0aac365944cec7678c2c8ff2e4b5ee37178dad4d531544be7e126343c7' 
  AND token = '4PZG7noIWYTh3s7/xPLSpHTdLG18PQE4FG0jX6Xw8xU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}