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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4781c1cfd31efff1c56e6ba3f777ef29d13afe0ca0caa3c8822c964845de8a12' 
  AND token = 'ecrXUTbj4Vy9Ztb4Wvb99p48zhzk2uBY07WWhhKJa/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}