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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25bc8c3a3558ed3c17006f846a1dc708ae824b90c8ccfa9075229552dcbc9ea9' 
  AND token = 'lzIUI++A9si/RbHVPJj1YN2H/vxaE2+fm125uxEIvaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}