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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '10870687658077c1a47f8fae86aeb3d1cc83331d821cc8986f5e8e014dbb049b' 
  AND token = 'zGbn8OjBJy7g27X7GOg/MoaTCwUggaOal3HLtjAuTFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}