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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6ade2c160bf444a80dedcb238fb54bb1977588ce8efb77720462e96b3f831eaa' 
  AND token = 'FtwebXwkgIKdigLisRKB/6wip+KD0zTHIwfYH5nlftM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}