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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '577189a7f28ea9df3d02ca9f85a74258b52dc31b474344d24bb0673dc0d1966b' 
  AND token = 'TWnk1jQ1UkcOHdWCZ/u+Yz64dL4bXRU2CFnx+3RmU0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}