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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f221a3baa1efddf7eb3d007cd1726364bd440171cf5e441b89e867e454c05193' 
  AND token = '5E++baIbWxih5EZTThTTTh3yy+nXypsqzE+Yvr1A52w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}