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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0ede93ee07b2f4cfd1c2d9000c74616b18e7948f79ab16efc1fe2726ffb3bc8c' 
  AND token = 'UGxATQG40DhNCSbY6hnkgekGjxiLt5Mpkv3wJBed/i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}