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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e3b99caa6dbe0edcf9545cc540a517d7fbe86616f49738d79e55c845874c045' 
  AND token = '+lpQdIBguhxRgNeeedid3rf4w54eupm7xABiewhsjbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}