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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '05ab74c8a8224474c4037d064955468bb1d61c0f0e8c3629a08ea2d0eca10327' 
  AND token = 'dCEqvEydzH77UUxB8pyyTks08hKeCCC3a5aTzKpOoZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}