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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6074a43995d8efaa2edcf114fb348816664edce53df0f186ab1284bc09aa2109' 
  AND token = 'JGTFEwPT7Ep80sF3szP834Ux7+swQcBmIpMDIeCtEsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}