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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '742399b481a1510991cf6c337bca2e89f5647120fe391802c47fecb66ac21b9d' 
  AND token = '0YQZsiHiSlJJRW7sEUfpJNTWxCld91VPLenmE6xz5ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}