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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cb8c28fab73f18e1d2eaf24cff2a2dd19a67f025b15c2cf60816bec585a2cdb1' 
  AND token = 'lF1Ga9S2ThFuBZaGdZ5pjrNjLOhxUSPamePD4YpoxHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}