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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '61b18601aa458a5fb238b3df9f6cb6932ad9e8dabb09f476221729d7e9babc23' 
  AND token = '2sCqignwbhWgDMtDBeagiIDeMQbEXYXXV0dEigj+DUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}