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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22f2d5aeb0827c33efb3b08c51d8405fe76458155ada0a55a2b8e5630370fd99' 
  AND token = 'g4/RrrfrV48WN3kqFaEGRsT7stBZnQsC39xvVz0HRso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}