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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b3774ed1708b53634110d31b42382dd76256fc98d427e28acfef602a177c542' 
  AND token = '0Sm5bTewvZZZ3DFIFa702RYfAQL7BDTvzjLfUCXCcow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}