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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c693292ad73fcb01680eaab3b9f7ff45a414e37ee194dfdd0bfaacc27a18d0f6' 
  AND token = 'nec7iD1mNYQ5phG8xQWTzv7m/IN5UEMjQpncCa3WFxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}