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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cc647b2f9c45d8c565d4921a5fd90afa161c12b5cf60964e91dc9d9c67a424f6' 
  AND token = '12U4HRDYWR95MKH01gIsaZ/wotVwhESq0wsKT+Z4hfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}