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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f5e872be9e3bfb963fd734a561ce63b9344ca1f66e07caae673d6a2109115510' 
  AND token = '49OhruStD6Yq2+T8ERpkA7o9nAgTy6AFYmDF3mzZ27E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}