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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8f477012139aff0849389e676e01e80b5c5dbcd79fdbf8a21b7e012bc46e07fb' 
  AND token = 'McbVmt3wmcO/VzePyQGAJaQUTY/Ub21nbVU5a/x8KPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}