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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3ed4393694d858b88e3dd4fc80cd3ae717ec221f5b656369eaa345306d50dc9c' 
  AND token = 'JWA3YQoVa/2yt0wQniJ1+RZKwbBNxbbXn534oscc5Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}