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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '16de158352d8e8716eec37d17945c343b233c8a6044c30b39cf656199e01273c' 
  AND token = 'QD6pUU54Cd7qiXKHdNZU5rrZtzxJ3FBzu2YxwCtozMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}