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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e160985b28133054363b3206958930bca3b90936e48210bfe30c83ada745b6f9' 
  AND token = 'OiKSjsWV9agokec2noansIo7RR+wPHxosmdAK57X3TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}