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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c21e9a3ea748d0c3d7a2b0ef96c76ba91f3ab99d8756e567fef005af5da61178' 
  AND token = 'VJ8zXa8wamUeYB1SixVaou9YTFCCtXExUrMgPVuIXM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}