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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '68cf83adaf3285c6591d2b3ac78b1a0e6b97a305b359f2d936b01c0ade67af15' 
  AND token = 'MR5xTFUf+W+Amnh9Rq50VF0Z8sSsyLy6rD9k5jyH8iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}