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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3338545db7c341702bb7cabb12c1bc2e12376d0febcbe4ab081139e90327c418' 
  AND token = 'WqvoIOjDgPQxEzlChDmhHQOwI9hwBUkek2EZb4vPeHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}