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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6305bb1928f0916544b3ea4d3a10a85f0dc24016f5ec7d3efd113d39b1a51f16' 
  AND token = 'Yjdr8y2CgN2H8TfQIkJQaT9YmLTooT+cRKAaBz9BNKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}