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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd78121fb22c73f9187c52b2e50bc86fc115d3ab659a442db8549c60a8c651562' 
  AND token = 'Lwv9fbiO9uRG4I7KQ680RCrhWAQ6N57aLaXlSB5Iz7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}