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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '389aceba7c27842c870e33396042a96c9e5d7af17134c6a3212e2bab42bf9190' 
  AND token = 'ZKp50gfLYEmC28xd/dPEb1Tbm1xsbzQDXhx8HfIBTOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}