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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6d1e9e92672722f2730eb597b56b89b97e734be27eb1a01adc7766f48b4a6100' 
  AND token = 'PiPhl8KvlAT7j7ajNhpRAe+hoqLAhv5yPRQ/7Z1J5JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}