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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f1cffb1b9845b749bb43de4b8dd136f5458598b8b64daca65f90065e20065cab' 
  AND token = '2kJxBjsAfeLV25dS1igy/k0143+d9q+Ay3W+YP4xKO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}