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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fc0434e3ac95e423ccf1f31e38d182e46c7aafaa7500758770b3737df94f4cea' 
  AND token = 'IRS0MTeKg3PmHTDlkFy//vwrY8wp0F9k8owWE450G3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}