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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '54df21b0f93c21ad56575029c0f255bdd776874bdc09ee5aeac2364a8a13c02a' 
  AND token = '9ENxWUAOgNGi1zqY4FYy8N1RCs46oNS5cpQooeRw6hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}