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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '78c321cdcc3acdac2d91d5effb9e8a65da8d27f7ee3a43122061f555d676b243' 
  AND token = 'NgeP3QOK5f0YWqfh2uvhfgpdhaeADsz+BSV5OBkXEtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}