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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5d41c8a0d2440d9ddae8b8ab795b0cff595be145dc55c952262fce5c070c6e65' 
  AND token = 'R5/7tS0/SEJDmPHKOYrwOga3u0KSqN4jU4vQoxyDx7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}