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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4597a7e4d90b3bb804d3eb1602ee181952dab8da33acbc9684f47f175a5a575c' 
  AND token = 'GvkGEsVO8LGaMQDyTvryoB1to9Sfl6X32DtXsyVeDF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}