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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '12f052acea70b021dad8d59df9351364151a7f2a703f3cf535341bac178aaf68' 
  AND token = 'xRR0Kvbl4+/N80YCzfpQ2bLvWbTrL0nAgMjYbPEymw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}